Studies and Projects

The named studies, trials and projects we run

This page lists the individual studies, cohorts, trials and innovation projects hosted at Mildmay Research Centre Uganda (MRCU). For the thematic areas and wider research programme that these projects sit within, see Research.

Clinical studies, trials and cohorts

Current and recent clinical research platforms

Interventional and observational studies conducted in a research environment supported by Mildmay Uganda Hospital.

Global Health EDCTP3 · Phase 4

PREGART

A randomized trial comparing dolutegravir and EFV400 during pregnancy and breastfeeding, with follow-up of mothers and infants.

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Paediatric and adolescent HIV cohort

UPART

An observational cohort studying routine HIV care, with sub-studies on dolutegravir outcomes and advanced HIV disease.

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NIH / NICHD · Randomized trial

GOALS

Goals for Adherence with Low-cost Incentives: a randomized controlled trial evaluating the impact of small airtime incentives on ART adherence among young people living with HIV in Kampala, using behavioural economics.

Pilot randomized trial

INMIND

Incentives and Reminders to Improve Long-term Medication Adherence: structured incentive and reminder models designed to support durable medication adherence behaviours.

Palliative care

GHAP

Piloting Children's Palliative Outcome Scale (C-POS) tools in paediatric life-threatening illness care to improve patient-centred outcome measurement.

AMBER Initiative · Immunology

AMBER

An international research initiative founded and scientifically led by Dr. Ramapraba Appanna and hosted by Mildmay Research Centre Uganda. AMBER advances B-cell immunology, antibody science and host-microbiome research to investigate infectious and non-communicable diseases, with particular emphasis on maternal and child health.

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MicroResearch International · Canada

MicroResearch

Locally led, community-focused studies developed by multidisciplinary teams of health workers, run in partnership with MicroResearch International (Dalhousie University and IWK Health Centre, Halifax). Teams take a proposal through international scientific review before ethics approval and implementation. About the partnership.

Implementation and public health projects

Funded implementation and health systems projects

Competitively funded projects supported by leading international research funders and implementation partners.

NIH / NIMH

Depression Care and PMTCT

Generating a model for integrating depression care into antenatal clinics to promote adherence to the PMTCT continuum and improve maternal and child health outcomes.

NIH

Gender-Transformative HIV Care

Developing and evaluating an innovative gender-transformative implementation strategy to improve HIV provider capacity for equitable HIV care in Uganda.

ViiV / GSK

Pediatric Breakthrough Partnership

Implementation research to understand the impact and effectiveness of the Pediatric Breakthrough Partnership across Mozambique, Nigeria and Uganda.

PEPFAR / CDC

Epidemic Control Project

A five-year epidemic control programme across eight districts of the Mubende region that generated longitudinal datasets which continue to inform community health programming.

Unitaid and FIND

PAHLCA-IRI

Comprehensive HIV programming delivered through a multi-principal-investigator consortium.

PENTA Foundation

PENTA / THRIVE

Multi-site paediatric HIV research, with MRCU participating as a satellite site.

Collaboration

Looking for a study partner, site or implementation team?

MRCU hosts clinical trials, implementation research, cohort studies and innovation projects across HIV, TB, maternal health, mental health and digital health.

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